Knowledge Gaps, Belief Gaps, Ideology, and Culture Wars

Gaps in Menopause Knowledge

The average middle aged woman goes through a volatile period of endocrine fluctuations as she passes through menopause and the stages that precede and follow it. Ovarian hormones are steroid hormones. They readily cross the cell and nuclear membranes and influence transcription of numerous genes. Such influences are tissue specific and state specific. In short, changes in ovarian hormones mean ...

The CLI Knowledge Gaps

Critical Limb Ischemia as a Public Health Crisis Peripheral artery disease (PAD) is one of the most common cardiovascular diseases and is associated with high short-term morbidity and mortality. It is the primary cause of lower extremity amputation throughout the world and is a powerful marker of advanced systemic atherosclerosis. Chronic critical limb ischemia (CLI) represents the most advance...

Closing the knowledge gaps.

Representing Knowledge Gaps Effectively

In knowledge acquisition, one typically encounters two difficult situations: First, there are times when the system requests information that, due to a lack of information, the user is not in a position to provide at the level of precision requested. Second, there are situations where the system cannot capture information at the level of precision the user wishes to provide. We describe the tec...

Child Psychopharmacology – Gaps in Knowledge

The rapid growth of child psychopharmacology has been nothing short of being phenomenal. Not only have the types of medications available increased dramatically, but so have their annual rates of production and prescription. But There is, however, inadequate research on the physiological and behavioural effects of psychoactive medications; their long term effects, the mechanisms of their action...